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学生对 University of California San Diego 提供的 Finding Hidden Messages in DNA (Bioinformatics I) 的评价和反馈

4.3
1,046 个评分

课程概述

Named a top 50 MOOC of all time by Class Central! This course begins a series of classes illustrating the power of computing in modern biology. Please join us on the frontier of bioinformatics to look for hidden messages in DNA without ever needing to put on a lab coat. In the first half of the course, we investigate DNA replication, and ask the question, where in the genome does DNA replication begin? We will see that we can answer this question for many bacteria using only some straightforward algorithms to look for hidden messages in the genome. In the second half of the course, we examine a different biological question, when we ask which DNA patterns play the role of molecular clocks. The cells in your body manage to maintain a circadian rhythm, but how is this achieved on the level of DNA? Once again, we will see that by knowing which hidden messages to look for, we can start to understand the amazingly complex language of DNA. Perhaps surprisingly, we will apply randomized algorithms, which roll dice and flip coins in order to solve problems. Finally, you will get your hands dirty and apply existing software tools to find recurring biological motifs within genes that are responsible for helping Mycobacterium tuberculosis go "dormant" within a host for many years before causing an active infection....

热门审阅

QL

Jul 26, 2017

The algorithms mentioned in this course are explained very well. But still a little bit of programming language is needed. Look forward to the advanced courses.

JN

Sep 22, 2020

Please be clear while explaining the course. it not clear what are they trying to explain and it takes a lot time for us to figure it out.

筛选依据:

51 - Finding Hidden Messages in DNA (Bioinformatics I) 的 75 个评论(共 265 个)

创建者 bob n

Jul 16, 2020

Thoroughly enjoyed the course. Was a big help to have taken the intro class first. Instructors did a reasonable job of leading one through the material. Would have preferred more lecture, less reading, but not enough to knock a star off the rating. Material well organized. As some with an engineering background, the biology was mostly well explained.

创建者 Iman N

Jul 16, 2021

It is a very useful course; however, it would be much better if the instructors recommend the "Biology Meets Programming: Bioinformatics for Beginners" course specially for Biologists who want to start this course. Although no programming experience was required during the course, being familiar with the basis of programming would be so helpful.

创建者 Ranakombu K K D S

Apr 11, 2020

A well-structured and amazing course that provides a wealth of knowledge in bioinformatics including an optional honors track for programming. Thoroughly enjoyed it and excited to continue with the rest of the Specialization! A big thank you to the creators of this brilliant course. Simply one of the best courses on Coursera!

创建者 Ajani c o

Sep 13, 2020

I am so overwhelmed. I learnt a whole lottttt. I learnt how to create motif logos, identify ori and terminus using skew diagrams, amongst others. As a biologist, I was really discouraged at the beginning because of the series of referring links, but I am happy that I could see the end of the course. Thanks for the content.

创建者 Manuel A

Jul 25, 2016

Very good course, but at the same time very hard. Unless you have quite a bit of experience programing, be prepared to spend at least 15 hours a week working on this class. The good news is that if you do spend that time, you will learn a lot.

创建者 Hercules P N

May 9, 2017

Excellent course. It can be tough at times but it is amazingly accessible to all who are genuinely interested. The final assignment was very well prepared and gave a real hands-on experience that puts the course into practice.

创建者 Krishnendu S

Mar 28, 2019

Exceptionally beautiful course. Must be for those want to start career in bioinformatics. But prior basic knowledge in any programming language would be appropriate if someone wants to extract every aspect of this course.

创建者 Alexandr D

May 13, 2022

The course is interesting and challenging. For successful completion, it is necessary to know the basics of Python well. So if you have no experience in programming at all, then you need to be prepared for difficulties.

创建者 Yasmine E H

Jul 4, 2020

I really liked this course and definitely learned a lot. However, I wish that more guidance was provided such as the professors, and not just the peers, answering our questions when Stepik's explanation was not enough.

创建者 Ordinary M

Aug 20, 2021

though sometimes hard to uderstand, definately improved my skills. i suggest to start this course with some knowledge in programming (in my case i had basic knowledge in python)

创建者 Valeriya K

Apr 13, 2020

Overall, the course is great. However, in the week 4, the quality of pseudocode is not as good, it is much harder to follow. Would love to have had a more extensive explanation.

创建者 Qianhao L

Jul 26, 2017

The algorithms mentioned in this course are explained very well. But still a little bit of programming language is needed. Look forward to the advanced courses.

创建者 Mihai P

Dec 4, 2017

Nice and recommended.

(The final exam was a bit tedious though, with many points repeatedly given simply for "uploading the logo" and not much creative leeway)

创建者 Ahmed A

Apr 30, 2020

Extremely helpful. This course is not limited to teaching us to use Bioinformatic Tools, it also helps us understand deeply the ways in which the tools work.

创建者 Ali J

Aug 17, 2019

Hard class

If you have problems, go ahead and take Biology Meets Programming: Bioinformatics (University of California San Diego)... Highly suggest that

创建者 Julian B N F d S

Aug 12, 2023

Great Course, there is a lot of material available to learn. The only thing i would change is that the final proyect takes a lot of time to be graded.

创建者 Andrew C

Mar 29, 2019

I feel this was a good introduction to bioinformatics. It can be a little confusing sometimes, but there was nothing I could not figure out in the end

创建者 Jeet N

Sep 23, 2020

Please be clear while explaining the course. it not clear what are they trying to explain and it takes a lot time for us to figure it out.

创建者 Oluwafemi O

Jul 15, 2020

I really enjoyed the course, most especially the code challenges in the honors track. Thanks to the tutors for this wonderful course!

创建者 Yousof Y

Dec 11, 2017

A GOOD START TO LEARN BIOINFORMATICS, AND ITS ALGORITHMS.

YOU SHOULD HAVE SOME PROGRAMMING EXPERIENCE FOR A BETTER UNDERSTANDING.

^_^

创建者 Sumant K

Oct 8, 2020

Excellent introduction of Bioinformatics to computer scientist. I am committed for the long haul now, on learning Bioinformatics.

创建者 Sonam N K 1

Aug 14, 2020

Loved how hands-on and interactive this course is! I learnt python side-by-side with this course, and it was definitely worth it!

创建者 Oscar J O R

Aug 13, 2018

Really nice and clear course. The hands-on learning is fundamental to create a smooth transition between algorithms and biology.

创建者 Valentýna P

Apr 1, 2018

Well prepared course although sometimes tough due to algorithmization tasks even for people with programming background.