Chevron Left
返回到 Epigenetic Control of Gene Expression

学生对 The University of Melbourne 提供的 Epigenetic Control of Gene Expression 的评价和反馈

4.8
836 个评分

课程概述

While the human genome sequence has transformed our understanding of human biology, it isn’t just the sequence of your DNA that matters, but also how you use it! How are some genes activated and others are silenced? How is this controlled? The answer is epigenetics. Epigenetics has been a hot topic for research over the past decade as it has become clear that aberrant epigenetic control contributes to disease (particularly to cancer). Epigenetic alterations are heritable through cell division, and in some instances are able to behave similarly to mutations in terms of their stability. Importantly, unlike genetic mutations, epigenetic modifications are reversible and therefore have the potential to be manipulated therapeutically. It has also become clear in recent years that epigenetic modifications are sensitive to the environment (for example diet), which has sparked a large amount of public debate and research. This course will give an introduction to the fundamentals of epigenetic control. We will examine epigenetic phenomena that are manifestations of epigenetic control in several organisms, with a focus on mammals. We will examine the interplay between epigenetic control and the environment and finally the role of aberrant epigenetic control in disease. All necessary information will be covered in the lectures, and recommended and required readings will be provided. There are no additional required texts for this course. For those interested, additional information can be obtained in the following textbook. Epigenetics. Allis, Jenuwein, Reinberg and Caparros. Cold Spring Harbour Laboratory Press. ISBN-13: 978-0879697242 | Edition: 1 The course will re-open in 2022....

热门审阅

HK

Nov 16, 2018

This course is well taught and some important concepts are repeated over and over again during the course so the concept lingers in the brain as if it was there already.

AL

Dec 10, 2016

Excellent course by an expert in the field. Full appreciation requires a background in biochemistry and genetics, but still a lot can be learned by anyone with interest.

筛选依据:

51 - Epigenetic Control of Gene Expression 的 75 个评论(共 229 个)

创建者 Anne L

May 2, 2017

This course gave an excellent overview of epigenetics including molecular mechanisms with multiple case studies and a focus on cancer in the last week. I learned a lot and feel more confident branching out into the field after taking this course.

创建者 Abhiyanta M

May 19, 2020

This course was really interesting and very informative. Each and every topic is explained with the help of diagram. Even the animations used was very very interesting. The presentation was very informative. It is very easy to understand.

创建者 Rhea J

May 20, 2020

The course proved to be very informative. My knowledge on the subject has definitely increased. This course has also refueled my interests towards this field. I thank the team, Coursera and Dr. Marnie Blewitt for this great experience!

创建者 EDUARDO R P

Sep 28, 2019

It is a somewhat complicated course even knowing a little about the subject, however it was an excellent course and I learned a lot. I discovered new topics and acquired new knowledge. Congratulations!

Thank you for sharing this course.

创建者 Antonina K

Mar 26, 2016

As far as we have no Genetic, no Epigenetic courses in our medical universities. I feel that I have a huge gap in my knowledge in this field. I am so happy that I can attend such interesting and necessary course. Thank you very much)

创建者 Claudia B

Mar 30, 2016

What can I say? An extremely complete course, very resourceful, dynamic and with great quality content from reliable sources. If you are interested in genetics, you will love this take on epigenetics; definitely worth it.

创建者 Vinicios A

Aug 13, 2017

This course is an incredible introduction to the Science of Epigenetics. Thanks to the course I've learnt a lot about Epigenetic and now I feel confident to read and understand all the papers in this field of knowledge.

创建者 salbiha 5

Jul 23, 2023

It is the best opportunity for students like me who want to pursue a career in research for cancer. It helped me a lot and provide me with a lot of information about Epigenetic Modifications In the context of Cancer

创建者 Hugo F

Oct 16, 2017

Really good course! The design of the last assignment is more close to what I believe online courses should do. It really challenges yourself to apply the knowledge acquired from lectures and reading material.

创建者 Paul S

Mar 30, 2019

Well organized and thought out. Developed the concepts well with clear examples from literature. Gave an understanding of the state of the field and where there are things that still need to be worked out.

创建者 Vanessa L

Mar 9, 2017

I really enjoyed this course it's really interesting and I learned a lot about epigenetics. I really liked the professor and the way she explained and really enjoyed the materials she suggested us to read.

创建者 Sydney G

Jan 23, 2023

Very informative, especially if you already have a background in genetics/molecular biology. I would recommend this to anyone who is thoroughly interested in the subject, as it covers a lot of material.

创建者 Mary M

Oct 1, 2018

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.

创建者 BARAIYA D H 1

Apr 24, 2020

It was very informative course and will help me in my future studies.In between week 3 was bit tough to understand and keep all things in mind. But overall course was amazing. Thank you.

创建者 Aditya D

May 12, 2020

Amazingly structured and delivered course by the entire team. Including a few practical assays or how to read some of the assay results related to epigenetic techniques would be welcome.

创建者 Boris M

Aug 14, 2017

One of the best organized and implemented courses I have taken so far. For someone who had barely any experience with epigenetics, I feel this gave me a proper introduction to the field.

创建者 HanuRam

Dec 18, 2016

A quintessential course for Genetics students all over the world. Very nicely prepared and elucidated by Dr. Marnie Blewitt .

Many many thanks to Dr. Marnie Blewitt & Coursera team.

创建者 Thomas W

Aug 24, 2017

Very informative! Before starting this course I didn't even know epigenetics was a word. Now I feel I have a very good grasp of the basics of one of the core concepts of genetics.

创建者 Dominika B

Sep 28, 2016

This was an AWESOME course. Really exciting, interesting, AND surprising, I never thought there's that much to talk about in epigenetics! I'm going to recommend it, definitely :)

创建者 Vinícius

Nov 24, 2020

Excellent course! The topic isn't an easy one, but Dr Marnie Blewitt was brilliant and her explanation is clear and very good. Besides that, this course provides good support.

创建者 Vasisht V S

Aug 8, 2018

A very informative course which starts from the basics and goes up all the way and the pace of the course is also perfectly set for anyone from professionals to first-timers.

创建者 Ziwen L

Dec 12, 2016

Well constructed course and carefully designed questions. It is very useful for someone with biological and/or biomedical background to expand their knowledge on epigenetics!

创建者 Alagbe O A

Nov 27, 2019

The lectures were enlightening and easy to follow and understand. there were also a lot of examples that made the lectures easy to understand. I totally loved and enjoyed it

创建者 Lusya M

Jun 19, 2016

The course is very interesting for those who like Genetics. The lectures are delivered in an understandable manner, and the motion pictures make everything clear right away.

创建者 Arthur V L

Dec 10, 2016

Excellent course by an expert in the field. Full appreciation requires a background in biochemistry and genetics, but still a lot can be learned by anyone with interest.