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学生对 The University of Melbourne 提供的 Epigenetic Control of Gene Expression 的评价和反馈

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834 个评分

课程概述

While the human genome sequence has transformed our understanding of human biology, it isn’t just the sequence of your DNA that matters, but also how you use it! How are some genes activated and others are silenced? How is this controlled? The answer is epigenetics. Epigenetics has been a hot topic for research over the past decade as it has become clear that aberrant epigenetic control contributes to disease (particularly to cancer). Epigenetic alterations are heritable through cell division, and in some instances are able to behave similarly to mutations in terms of their stability. Importantly, unlike genetic mutations, epigenetic modifications are reversible and therefore have the potential to be manipulated therapeutically. It has also become clear in recent years that epigenetic modifications are sensitive to the environment (for example diet), which has sparked a large amount of public debate and research. This course will give an introduction to the fundamentals of epigenetic control. We will examine epigenetic phenomena that are manifestations of epigenetic control in several organisms, with a focus on mammals. We will examine the interplay between epigenetic control and the environment and finally the role of aberrant epigenetic control in disease. All necessary information will be covered in the lectures, and recommended and required readings will be provided. There are no additional required texts for this course. For those interested, additional information can be obtained in the following textbook. Epigenetics. Allis, Jenuwein, Reinberg and Caparros. Cold Spring Harbour Laboratory Press. ISBN-13: 978-0879697242 | Edition: 1 The course will re-open in 2022....

热门审阅

NN

Aug 1, 2021

T​his is the best course on coursera, 10/10. I wish it was longer and I could take it all over again. you will need background knowledge for this course but it is an amazing course and I will miss it.

MM

Oct 1, 2018

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.

筛选依据：

201 - Epigenetic Control of Gene Expression 的 225 个评论（共 229 个）

创建者 dinesh r

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May 17, 2020

Excellent!

创建者 Mayookha M

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Nov 27, 2020

Excellent

创建者 ALBEIRO M M P

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Dec 27, 2016

Excellent

创建者 Daniel S

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Nov 14, 2016

Excelent!

创建者 19BBT041_Praveen.R

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May 20, 2020

The best

创建者 Carlos E

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Sep 22, 2017

Amazing!

创建者 Ilir S

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Dec 1, 2017

Awesome

创建者 Fall A

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Oct 11, 2017

good .

创建者 aya s

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May 2, 2019

great

创建者 Daniel F R R

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Apr 25, 2016

Nicee

创建者 Sandy P

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Sep 7, 2025

good

创建者 Hu N

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Feb 16, 2019

nice

创建者 Anubhav C

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Jun 11, 2018

This is an excellent introductory course in epigenetics, however, if the course had included few chapters in epigenetic modifications like acetylation, glycosylation, phosphorylation, etc. it would have been much more exciting. Nevertheless, the course is extremely lucid to follow, the tutoring is really insightful, the materials are well-structured, the instructions are well-laid and, the most importantly, the assignments are challenging.

创建者 Cristian C

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May 9, 2023

It was an interesting course, although, I would have preferred a better explanation of terms used in this course. Anywawy, overall, it is an excellent course which gives you an insight into Epigenetics

创建者 Alberto T

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Jun 23, 2016

Very clear explanations. Four star because I think that the part on X chromosome is too long and covered with too details respect to other topics.

创建者 Sohaila J

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May 27, 2017

Loved it. Very well structured and explained. I actually looked forward to completing lectures and readings every week.

创建者 Jayne G

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Aug 31, 2016

I really enjoyed this course, and as an Australian it is so exciting it comes form a domestic university. Thank you

创建者 Louis-Stéphane I L C

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May 29, 2020

Very interesting course covering many diverse aspects regarding epigenetics. Has been invaluable towards my PhD!

创建者 MEENA M 1

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May 18, 2020

The course was really very informative. But it would have been great if the subject was little more simplified.

创建者 丁雪松

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Dec 1, 2016

this course gave a general ideal about epigenetic control, and it is helpful to me, Thanks

创建者 Theodor S

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Dec 7, 2017

Very useful course for anyone who wants to get a deeper understanding of epigentics.

创建者 ubaid m

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May 7, 2017

this course too me to the highest of my knowledge. i think this course is remarkable

创建者 Echefu B E

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Jul 13, 2023

This is the right course towards gaining deep insight about epigenetics

创建者 Renate L

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Oct 21, 2021

sehr gute Inhalte, die Übersetzung ist nicht immer bestens

创建者 Yvonne A

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Sep 22, 2016

Difficult course but very worthwhile your time