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学生对 Icahn School of Medicine at Mount Sinai 提供的 Introduction to Systems Biology 的评价和反馈

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575 个评分

课程概述

This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems? The course will develop multiple lines of reasoning to answer the questions listed above. Two major reasoning threads are: the design, execution and interpretation of multivariable experiments that produce large data sets; quantitative reasoning, models and simulations. Examples will be discussed to demonstrate “how” cell- level functions arise and “why” mechanistic knowledge allows us to predict cellular behaviors leading to disease states and drug responses....

热门审阅

NA

Jun 15, 2020

A fantastic introductory course. One should really treat this as an overview that needs to be followed by further study.

MS

Sep 19, 2023

Module 1: Introduction was a challenge. The lecture verbal dialogue needs to be edited in the corresponding "printed" version.

筛选依据：

101 - Introduction to Systems Biology 的 117 个评论（共 117 个）

创建者 Alejandro V (

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May 29, 2017

Great new area to explore and study, however some subjects were not explained adequately.

创建者 Adam C

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Oct 12, 2024

Great introductory course. Needs some more material on the actual reaction equations.

创建者 James H

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Jun 20, 2024

Challenging for someone not trained in the biological sciences, but still possible.

创建者 LE X H

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Aug 5, 2024

The topic is helful for beginer into new field of study like me

创建者 Md. M H

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Feb 26, 2016

Very very informative course for the beginners like me!

创建者 Jiho C

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Mar 9, 2017

Good lecture, but not systematic curriculum

创建者 Mariya P

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Nov 25, 2019

Instructor is very hard to engage with.

创建者 Amir B

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Jan 1, 2016

a bit to hard for an introduction cours

创建者 Arpita R

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Aug 2, 2022

Excellent course work!

创建者 Kang c

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Jun 14, 2016

A very useful course!

创建者 Chalasani S S N

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Apr 10, 2019

useful

创建者 Tom S

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Jan 24, 2023

some subjects are mentioned without enough explanation. It seems that the goal is to understand the big picture but sometimes hard to follow without understand the micro details.

创建者 Karl D

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Jul 26, 2017

Good overview of systems biology, but the graded tests are somewhat difficult to understand for someone without a biology background such as myself.

创建者 Connie N

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Oct 1, 2020

Really interesting content, but could use a rework on formatting, style, and clarity.

创建者 Alan R d F K M

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Jan 20, 2020

Could give more basic information about systems theory

创建者 Milena J

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Feb 12, 2016

The lectures were somehow chaotic.

创建者 Mainak B

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Feb 23, 2020

Tough and brain storming